Error message
User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 96) __TwigTemplate_1542e28ecd23eb9f51b3cf19a0f0d78b->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 556) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 77) __TwigTemplate_71870a835705e73bfa6156daf8f36212->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 96) __TwigTemplate_1542e28ecd23eb9f51b3cf19a0f0d78b->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 513) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 166) __TwigTemplate_71870a835705e73bfa6156daf8f36212->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 96) __TwigTemplate_1542e28ecd23eb9f51b3cf19a0f0d78b->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 139) __TwigTemplate_033accae3f1ee663fc609d06659d9dce->block_content() (Line: 446) Twig\Template->yieldBlock() (Line: 115) __TwigTemplate_033accae3f1ee663fc609d06659d9dce->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 513) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 166) __TwigTemplate_71870a835705e73bfa6156daf8f36212->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 96) __TwigTemplate_1542e28ecd23eb9f51b3cf19a0f0d78b->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)User warning: mkdir(): Permission Denied in Drupal\Component\PhpStorage\FileStorage->createDirectory() (line 125 of core/lib/Drupal/Component/PhpStorage/FileStorage.php).
Drupal\Component\PhpStorage\FileStorage->createDirectory() (Line: 73) Drupal\Component\PhpStorage\FileStorage->ensureDirectory() (Line: 66) Drupal\Component\PhpStorage\MTimeProtectedFastFileStorage->save() (Line: 116) Drupal\Core\Template\TwigPhpStorageCache->write() (Line: 410) Twig\Environment->loadTemplate() (Line: 370) Twig\Environment->load() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 556) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 501) Drupal\Core\Template\TwigExtension->escapeFilter() (Line: 96) __TwigTemplate_1542e28ecd23eb9f51b3cf19a0f0d78b->doDisplay() (Line: 402) Twig\Template->yield() (Line: 386) Twig\Template->render() (Line: 51) Twig\TemplateWrapper->render() (Line: 35) Drupal\Core\Template\TwigThemeEngine->renderTemplate() (Line: 428) Drupal\Core\Theme\ThemeManager->render() (Line: 500) Drupal\Core\Render\Renderer->doRender() (Line: 230) Drupal\Core\Render\Renderer->render() (Line: 162) Drupal\Core\Render\MainContent\HtmlRenderer->{closure:Drupal\Core\Render\MainContent\HtmlRenderer::renderResponse():157}() (Line: 634) Drupal\Core\Render\Renderer::{closure:Drupal\Core\Render\Renderer::executeInRenderContext():634}() Fiber->start() (Line: 635) Drupal\Core\Render\Renderer->executeInRenderContext() (Line: 157) Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse() (Line: 90) Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray() (Line: 246) Symfony\Component\EventDispatcher\EventDispatcher::{closure:Symfony\Component\EventDispatcher\EventDispatcher::optimizeListeners():241}() (Line: 206) Symfony\Component\EventDispatcher\EventDispatcher->callListeners() (Line: 56) Symfony\Component\EventDispatcher\EventDispatcher->dispatch() (Line: 188) Symfony\Component\HttpKernel\HttpKernel->handleRaw() (Line: 76) Symfony\Component\HttpKernel\HttpKernel->handle() (Line: 53) Drupal\Core\StackMiddleware\Session->handle() (Line: 48) Drupal\Core\StackMiddleware\KernelPreHandle->handle() (Line: 28) Drupal\Core\StackMiddleware\ContentLength->handle() (Line: 32) Drupal\big_pipe\StackMiddleware\ContentLength->handle() (Line: 203) Drupal\page_cache\StackMiddleware\PageCache->fetch() (Line: 140) Drupal\page_cache\StackMiddleware\PageCache->lookup() (Line: 89) Drupal\page_cache\StackMiddleware\PageCache->handle() (Line: 48) Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle() (Line: 51) Drupal\Core\StackMiddleware\NegotiationMiddleware->handle() (Line: 53) Drupal\Core\StackMiddleware\AjaxPageState->handle() (Line: 54) Drupal\Core\StackMiddleware\StackedHttpKernel->handle() (Line: 745) Drupal\Core\DrupalKernel->handle() (Line: 19)
NIOSH Hazardous Drugs 2024 — Reference for Nurses
v1.0.0 · NIOSH 2024 · Built-in · Last reviewed Dec 2024
NIOSH Hazardous Drugs 2024
CDC NIOSH List of Hazardous Drugs in Healthcare Settings · Tables 1 & 2 · Essential for oncology, chemo, and reproductive health nurses
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Table 1 — Drugs with manufacturer special handling information (MSHI) in package insert AND/OR classified as carcinogens by NTP or IARC. Requires full USP <800> compliance.
Table 2 — All other hazardous drugs meeting NIOSH criteria. May include reproductive/developmental hazards. Eligible for Assessment of Risk under USP <800>.
1 drug found for "cladribine"
Cladribine
Table 1
AHFS Class: Antineoplastic
⚠ Reproductive/Developmental HazardMSHI Required
PPE & Handling: Double gloves, gown, eye protection.
Source: CDC NIOSH List of Hazardous Drugs in Healthcare Settings, 2024 · cdc.gov/niosh · Published December 2024 · Supersedes 2016 list · 25 drugs added, 7 removed · Table 3 eliminated — drugs redistributed to Tables 1 & 2 · For occupational safety reference only — always follow your institution's hazardous drug policy and USP <800> requirements · Next expected update: ~2026