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Chronic Obstructive Pulmonary Disease
Respiratory
Clinical reference
Chronic Obstructive Pulmonary Disease
COPD is a progressive airflow obstruction from emphysema and chronic bronchitis. Exacerbations drive hospitalizations. GOLD staging guides management.
Terms
2
ICD-10
4
Evidence
5
Trials
8
Latest evidence
Latest evidence
Antioxidants as Therapeutic Tools in the Management of COPD: A Systematic Review with Meta-Analysis.
Impact of Frailty on Activities of Daily Living and Length of Hospitalization in Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
Does mental illness history affect primary care chronic disease management in older adults? A population-based propensity score-matched study.
Investigating the feasibility of an 8-week mindful breathing programme on breathlessness and self-efficacy in chronic obstructive pulmonary disease: an open-label study.
Core official overview
What this condition is
What is COPD (chronic obstructive pulmonary disease)?COPD (chronic obstructive pulmonary disease) is a group of lung diseases that make it hard to breathe and get worse over time.Normally, the airways and air sacs in your lungs are elastic or stretchy. When you breathe in, the airways bring air to the air sacs. The air sacs fill up with air, like a small balloon. When you breathe out, the air sacs deflate, and the a…
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Common tests
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Recruiting clinical trials
Additional official research
Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease
The STOP-COPD trial is a randomized, patient-blinded, prehospital clinical trial designed to evaluate the effect of titrated oxygen therapy compared to standard oxygen treatment in patients with suspected acute exacerbation of chronic obst…
COPD-ICU Multicentre Prospective Observational Register
COPD is one of the leading causes of morbidity, mortality and health care utilisation worldwide. Currently, COPD is the third leading cause of death worldwide and is therefore a major public health problem. Projections show an increase in…
Sputum-guided Treatment With Comprehensive Care Management in COPD - A Randomized-controlled Trial
Chronic obstructive pulmonary disease (COPD) is a lung condition affecting 1 in 6 Canadians and does not have a cure. Flare-ups of COPD are the most common reason someone goes to hospital in Canada. This is made worse because within 30-day…
Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease
Exacerbations of chronic obstructive pulmonary disease (COPD) are unfavourable events in the course of disease for most COPD patients. Published evidence indicates a significant impact of exacerbations, especially if frequent, on patients'…
Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis
The purpose of this study is to determine whether nasal high flow is non inferior to non invasive ventilation (NIV) in the early treatment of patients with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) and hypercapn…
Effect of Spacer Use on Exacerbation Risk in High-Risk Older Adults With Chronic Airway Diseases Receiving Triple Therapy
This study evaluates whether adding a spacer device to triple inhaled therapy (ICS/LABA/LAMA via pMDI) can reduce acute exacerbations in elderly patients (≥65 years) with stable chronic airway diseases (COPD or asthma) who are classified a…
Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets
The goal of this study is to examine exacerbations of chronic obstructive pulmonary disease (COPD) caused by a common cold virus called rhinovirus, to identify new treatments. Exacerbations are flare-ups of respiratory symptoms which are a…
Effects of COPD Standardized Management on COPD Exacerbation
This is a multi-center, parallel-group,cluster randomised trial involving secondary hospitals across China. The objective is to evaluate the effect of COPD on reducing moderate-to-severe exacerbations during 12 months follow-up in primary-…
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COPD
What is COPD (chronic obstructive pulmonary disease)?COPD (chronic obstructive pulmonary disease) is a group of lung diseases that make it hard to breathe and get worse over time.Normally, the airways and air sacs in your lungs are elastic or stretchy. When you breathe in, the airways bring air to the air sacs. The air sacs fill up with air, like a small balloon. When you breathe out, the air sacs deflate, and the a…
Emphysema
What is emphysema?Emphysema is a type of COPD (chronic obstructive pulmonary disease). COPD is a group of lung diseases that make it hard to breathe and get worse over time. The other main type of COPD is chronic bronchitis. Most people with COPD have both emphysema and chronic bronchitis, but how severe each type is can be different from person to person.Emphysema affects the air sacs in your lungs. Normally, these…
Chronic Bronchitis
What is chronic bronchitis?Chronic bronchitis is a type of COPD (chronic obstructive pulmonary disease). COPD is a group of lung diseases that make it hard to breathe and get worse over time. The other main type of COPD is emphysema. Most people with COPD have both emphysema and chronic bronchitis, but how severe each type is can be different from person to person.Chronic bronchitis is inflammation (swelling) and ir…
Heart Failure
What is heart failure?Heart failure means that your heart can't pump enough oxygen-rich blood to meet your body's needs. Heart failure doesn't mean that your heart has stopped or is about to stop beating. But without enough blood flow, your organs may not work well, which can cause serious problems.Heart failure can affect one or both sides of your heart:With right-sided heart failure, your heart is too weak to pump…