Traumatic Brain Injury
Traumatic Brain Injury
TBI ranges from mild concussion (GCS 13-15) to severe (GCS ≤8). Primary injury from impact; secondary injury from edema, hypoxia, hypotension. Neuroprotective care targets ICP <20, CPP >60.
Latest evidence
Ceftriaxone therapy attenuates brain trauma in rats by affecting glutamate transporters and neuroinflammation and not by its antibacterial effects.
The neuroprotective effect of quetiapine in critically ill traumatic brain injury patients.
36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
What this condition is
What is traumatic brain injury (TBI)?Traumatic brain injury (TBI) is a sudden injury that causes damage to the brain. It may happen when there is a blow, bump, or jolt to the head. This is a closed head injury. A TBI can also happen when an object penetrates the skull. This is a penetrating injury.Symptoms of a TBI can be mild, moderate, or severe. Concussions are a type of mild TBI. The effects of a concussion can…
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Additional official research
Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics
Narrative: Worldwide, traumatic brain injury (TBI) is a leading cause of death and disability among children and adolescents. The Investigators aim to test whether pediatric TBI treatment guided by invasive intracranial pressure monitoring…
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