Multiple Sclerosis

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Neurology Clinical reference

Multiple Sclerosis

MS is an autoimmune demyelinating CNS disease. RRMS (most common): relapsing-remitting. Presents with optic neuritis, sensory/motor deficits, bladder dysfunction. DMTs reduce relapse rate.

MS multiple sclerosis RRMS SPMS PPMS relapsing-remitting MS

Terms

ICD-10

Evidence

Trials

Latest evidence

No evidence articles returned for this search yet.

Core official overview

What this condition is

Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include:Visual disturbancesMuscle weaknessTrouble with coordination and balanceSensations such as numbness, prickling, or…

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Condition family & coding

Terms and documentation support

Condition matches & synonyms

Terms

Related diagnostic names, synonyms, and documentation wording that may appear in clinical references and charting.

Multiple sclerosis

ICD-10 quick links

Codes

For study support, terminology recognition, and documentation language.

G35.D Multiple sclerosis, unspecified G35.A Relapsing-remitting multiple sclerosis G35.B0 Primary progressive multiple sclerosis, unspecified G35.B1 Active primary progressive multiple sclerosis G35.C0 Secondary progressive multiple sclerosis, unspecified G35.C1 Active secondary progressive multiple sclerosis G35.B2 Non-active primary progressive multiple sclerosis G35.C2 Non-active secondary progressive multiple sclerosis

Common tests

Tests performed

MRI brain and spine with gadolinium (McDonald criteria) CSF analysis (oligoclonal bands) Visual evoked potentials CBC BMP Vitamin D level JC virus antibody (Natalizumab)

Common medications

Recognize the drug and the class

Beta-interferons: IFN-β1a, IFN-β1b Glatiramer acetate Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Siponimod Cladribine Methylprednisolone (acute relapse)

Related nursing diagnoses

NANDA diagnoses & care plans

Use these direct links to open nursing diagnoses and care-plan support related to Multiple Sclerosis.

Fatigue Impaired Physical Mobility Urinary Incontinence Impaired Sensory Perception Depression (risk)

Recruiting clinical trials

Additional official research

RECRUITING N/A

Adverse Childhood Experiences in Patients With MS: Impact on Quality of Life and on Coping Strategies Towards the Disease and Its Treatment

NCT06718920

The goal of this observational study is to evaluate the presence of adverse childhood experiences (ACE) in patients with Multiple Sclerosis. The main questions it aims to answer are: * Does the presence of ACE impact on quality of life of…

RECRUITING N/A

The Effect of Autologous Hematopoietic Stem Cell Transplantation on the Lower Urinary Tract Function Related to QoL in MS Patients

NCT06218927

Academic research project monitoring the effect of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) on multiple sclerosis-associated lower urinary tract symptoms.

RECRUITING PHASE3

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

NCT04047628

This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Ava…

RECRUITING N/A

Ocrevus Zunovo for MS: Mixed Methods

NCT07710105

Ocrevus Zunovo implementation, feasibility, acceptability, patient satisfaction, treatment persistence, and impact on MS disease outcomes will be analyzed in this mixed methods study. This study will incorporate clinical data and questionn…

Official education links

Plain-language study support

Useful for plain-language reinforcement and quick review.

Multiple Sclerosis Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include:Visual disturbancesMuscle weaknessTrouble with coordination and balanceSensations such as numbness, prickling, or… Cannabis What is cannabis?Cannabis, also known as marijuana, is a green, brown, or gray mixture of dried parts from the cannabis plant. The plant contains chemicals that affect the brain and can change how you feel or think.The main active chemicals are cannabinoids, including:THC (tetrahydrocannabinol), which causes the "high"CBD (cannabidiol), which does not cause a highHow do people use cannabis?There are many ways that p… Fatigue What is fatigue?Fatigue is a feeling of weariness, tiredness, or lack of energy. It can interfere with your usual daily activities. Fatigue can be a normal response to physical activity, emotional stress, boredom, or lack of sleep. But sometimes it can be a sign of a mental or physical condition. If you have been feeling tired for weeks, contact your health care provider. They can help you find out what's causing yo… Health Problems in Pregnancy What are health problems in pregnancy?A health problem in pregnancy is any disease or condition that could affect your health or the health of your fetus. Some health problems may make it more likely that you will have a high-risk pregnancy. A high-risk pregnancy is one in which you, your fetus, or both are at higher risk for health problems than in a typical pregnancy.But just because you have health problems, it d…