Gout

Body Systems › Musculoskeletal System › Gout
MSK Clinical reference

Gout

Gout is uric acid crystal deposition in joints. Classic: podagra (first MTP). Attacks are exquisitely painful. Chronic gout causes tophi and renal stones. Urate-lowering therapy prevents recurrence.

gout gouty arthritis hyperuricemia podagra tophi
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ICD-10
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Evidence
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Trials
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Latest evidence

Latest evidence

Core official overview

What this condition is

What is gout?Gout is a common type of inflammatory arthritis. It causes pain, swelling, and redness in one or more joints. It usually happens as a flare, which can last for a week or two and then gets better. The flares often begin in your big toe or a lower limb.What causes gout?Gout happens when too much uric acid (urate) builds up in your body over a long time. Uric acid is a waste product your body makes when it…

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Common tests

Tests performed

Joint aspiration (negatively birefringent crystals — gold standard) Serum uric acid CBC BMP Urinalysis (uric acid stones) X-rays (soft tissue tophi, erosions)
Common medications

Recognize the drug and the class

Acute: Colchicine 1.2mg PO then 0.6mg 1h later (first-line) Acute: NSAIDs (indomethacin 50mg TID) if GFR >30 Acute: Prednisone (GFR <30 or NSAID/colchicine contraindicated) ULT: Allopurinol start 100mg/day, titrate to uric acid <6 mg/dL ULT: Febuxostat (Uloric) Refractory: Pegloticase IV infusion
Related nursing diagnoses

NANDA diagnoses & care plans

Use these direct links to open nursing diagnoses and care-plan support related to Gout.

Acute Pain Impaired Physical Mobility Deficient Knowledge Non-Compliance
Official education links

Plain-language study support

Useful for plain-language reinforcement and quick review.

Gout What is gout?Gout is a common type of inflammatory arthritis. It causes pain, swelling, and redness in one or more joints. It usually happens as a flare, which can last for a week or two and then gets better. The flares often begin in your big toe or a lower limb.What causes gout?Gout happens when too much uric acid (urate) builds up in your body over a long time. Uric acid is a waste product your body makes when it…