Heparin-Induced Thrombocytopenia

Body Systems › Hematology / Blood System › Heparin-Induced Thrombocytopenia
Hematology Clinical reference

Heparin-Induced Thrombocytopenia

HIT is antibody-mediated platelet activation by heparin-PF4 complexes causing paradoxical thrombosis. Platelet drop ≥50% 5-14 days after heparin. Stop ALL heparin immediately — use alternative anticoagulant.

HIT heparin-induced thrombocytopenia HITT
Terms
0
ICD-10
4
Evidence
5
Trials
0
Latest evidence

Latest evidence

Condition family & coding

Terms and documentation support

Condition matches & synonyms

Terms

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ICD-10 quick links

Codes

For study support, terminology recognition, and documentation language.

D75.829 Heparin-induced thrombocytopenia, unspecified D75.821 Non-immune heparin-induced thrombocytopenia D75.822 Immune-mediated heparin-induced thrombocytopenia D75.828 Other heparin-induced thrombocytopenia syndrome
Common tests

Tests performed

4T score (clinical pre-test probability) Heparin-PF4 ELISA antibody Serotonin release assay (gold standard) CBC (trend) Coagulation studies Duplex ultrasound (thrombosis screen)
Common medications

Recognize the drug and the class

STOP ALL HEPARIN (including line flushes/LMWH) Argatroban (DTI — preferred hepatic dosing) Bivalirudin Fondaparinux (off-label) Warfarin: Add ONLY after platelets >150,000 Do NOT give platelets (fuels thrombosis)
Related nursing diagnoses

NANDA diagnoses & care plans

Use these direct links to open nursing diagnoses and care-plan support related to Heparin-Induced Thrombocytopenia.

Risk for Injury (thrombosis/bleeding) Deficient Knowledge Anxiety