Anticoagulation Management

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Hematology Clinical reference

Anticoagulation Management

Anticoagulation therapy for VTE prevention, AF stroke prophylaxis, and mechanical valves. DOACs (direct oral anticoagulants) have largely replaced warfarin. Reversal agents are available for all major DOACs.

anticoagulation blood thinners warfarin DOACs direct oral anticoagulants anticoagulant therapy
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Core official overview

What this condition is

What are blood thinners?Blood thinners are medicines that prevent blood clots from forming. They do not break up clots that you already have. But they can stop those clots from getting bigger. It's important to treat blood clots, because clots in your blood vessels and heart can cause heart attacks, strokes, and blockages. Who needs blood thinners?You may need a blood thinner if you have:Certain heart or blood vesse…

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Common tests

Tests performed

INR (warfarin monitoring — therapeutic 2-3) Anti-Xa level (LMWH monitoring in renal disease/obesity) aPTT (UFH monitoring) CBC BMP (renal function — DOAC dosing) Anti-Xa calibrated for specific DOAC
Common medications

Recognize the drug and the class

Warfarin (Coumadin) — INR 2-3; reversal: Vitamin K + 4F-PCC Apixaban (Eliquis) — reversal: Andexanet alfa Rivaroxaban (Xarelto) — reversal: Andexanet alfa Dabigatran (Pradaxa) — reversal: Idarucizumab (Praxbind) Enoxaparin (Lovenox) — reversal: Protamine (partial)
Related nursing diagnoses

NANDA diagnoses & care plans

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Risk for Bleeding Deficient Knowledge Non-Compliance Risk for Injury
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Blood Thinners What are blood thinners?Blood thinners are medicines that prevent blood clots from forming. They do not break up clots that you already have. But they can stop those clots from getting bigger. It's important to treat blood clots, because clots in your blood vessels and heart can cause heart attacks, strokes, and blockages. Who needs blood thinners?You may need a blood thinner if you have:Certain heart or blood vesse…