Cardiovascular
Clinical reference
Hyperlipidemia
Hyperlipidemia is elevated blood lipids (LDL, triglycerides) or low HDL. Primary cardiovascular risk factor. Treatment based on 10-year ASCVD risk calculation.
hyperlipidemia
dyslipidemia
high cholesterol
hypercholesterolemia
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Core official overview
What this condition is
What is cholesterol?Cholesterol is a waxy, fat-like substance that's found in all the cells in the body. The liver makes cholesterol, and it is also in some foods, such as meat and dairy products. The body needs some cholesterol to work properly. But if your child or teen has high cholesterol (too much cholesterol in the blood), it can stick to the walls of their arteries and narrow or even block the arteries. This…
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Recruiting clinical trials
Additional official research
RECRUITING
NA
NCT06684106
The purpose of this clinical trial is to understand whether the drug Ursodeoxycholic acid (UDCA) can prevent glucose intolerance in participants with hyperlipidemia who are taking statins. It will also assess the safety of UDCA. The primar…
RECRUITING
NA
NCT06603363
INTENSE Trial is a prospective, double-blind, randomized, placebo-controlled, single-center study with two arms (40 mg intensified statin therapy vs matching placebo for rosuvastatin) among statin-naive patients referred to coronary CT ang…
RECRUITING
N/A
NCT07742488
The goal of this study is to understand whether statin therapy, a common lipid-lowering therapy, may improve the coagulation profile of menopausal women with hypercholesterolemia undergoing hormone replacement therapy with oral estroproges…
RECRUITING
PHASE4
NCT05845424
The aim of this study is to compare safety and efficacy between the aggressive treatment with combination of high-intensity statin and ezetimibe and the current standard lipid lowering treatment in asymptomatic patients with presence of co…
RECRUITING
NA
NCT07359105
Statins are the cornerstone of cardiovascular disease (CVD) prevention through the lowering of low-density lipoprotein cholesterol (LDL-C). While the benefits of intensive LDL-C lowering are well-established for secondary prevention, evide…
RECRUITING
NA
NCT07524101
The ULTRA-CKD trial is a prospective, randomized, open-label, multicenter trial designed to compare the efficacy and safety of moderate-intensity statin plus ezetimibe combination therapy versus high-intensity statin monotherapy in patient…
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Plain-language study support
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High Cholesterol in Children and Teens
What is cholesterol?Cholesterol is a waxy, fat-like substance that's found in all the cells in the body. The liver makes cholesterol, and it is also in some foods, such as meat and dairy products. The body needs some cholesterol to work properly. But if your child or teen has high cholesterol (too much cholesterol in the blood), it can stick to the walls of their arteries and narrow or even block the arteries. This…
Cholesterol
What is cholesterol?Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your body needs some cholesterol to make hormones, vitamin D, and substances that help you digest foods. Your body makes all the cholesterol it needs. Cholesterol is also found in foods from animal sources, such as egg yolks, meat, and cheese.If you have too much cholesterol in your blood, it can combine with ot…
How to Lower Cholesterol
What is cholesterol?Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your body needs some cholesterol to work properly. But if you have too much of it in your blood, it can stick to the walls of your arteries and narrow or even block them. This puts you at risk for coronary artery disease and other heart diseases.Cholesterol is made by your liver. It travels through the blood on…
Cholesterol Levels: What You Need to Know
What is cholesterol?Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your body needs some cholesterol to work properly. But if you have too much of it in your blood, it can stick to the walls of your arteries and narrow or even block them. This puts you at risk of coronary artery disease and other heart diseases.How do you measure cholesterol levels?A blood test called a lipoprot…
