Systemic Lupus Erythematosus

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Autoimmune Clinical reference

Systemic Lupus Erythematosus

SLE is a multisystem autoimmune disease. SLICC/ACR criteria. Major manifestations: malar rash, nephritis, arthritis, serositis, cytopenias, neuropsychiatric lupus. Anti-dsDNA and low complement track disease activity.

SLE lupus systemic lupus lupus nephritis
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ICD-10
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Evidence
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Trials
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Latest evidence

Latest evidence

Core official overview

What this condition is

What is lupus?Lupus is a chronic (long-lasting) type of autoimmune disease. Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain.There are several types of lupus:Systemic lupus erythematosus (SLE) is the most common type. It can be mild o…

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Condition family & coding

Terms and documentation support

Condition matches & synonyms

Terms

Related diagnostic names, synonyms, and documentation wording that may appear in clinical references and charting.

Systemic lupus erythematosus

ICD-10 quick links

Codes

For study support, terminology recognition, and documentation language.

M32.9 Systemic lupus erythematosus, unspecified
Common tests

Tests performed

ANA (sensitive, not specific) Anti-dsDNA (specific, tracks activity) Anti-Sm (specific) Complement C3/C4 (low in active SLE) CBC (cytopenias) Urinalysis + protein:creatinine ratio BMP Anti-phospholipid antibodies Kidney biopsy (lupus nephritis)
Common medications

Recognize the drug and the class

Hydroxychloroquine (Plaquenil) — all SLE patients Prednisone (acute flares) Mycophenolate mofetil (nephritis induction/maintenance) Belimumab (Benlysta) — biologic Anifrolumab (Saphnelo) — biologic Voclosporin (Lupkynis) — lupus nephritis
Related nursing diagnoses

NANDA diagnoses & care plans

Use these direct links to open nursing diagnoses and care-plan support related to Systemic Lupus Erythematosus.

Fatigue Acute Pain Disturbed Body Image Risk for Infection Deficient Knowledge
Official education links

Plain-language study support

Useful for plain-language reinforcement and quick review.

Lupus What is lupus?Lupus is a chronic (long-lasting) type of autoimmune disease. Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain.There are several types of lupus:Systemic lupus erythematosus (SLE) is the most common type. It can be mild o… Joint Disorders What are joints?Your joints are places where two or more bones come together. Your shoulders, elbows, hips, knees, and knuckles are all joints. Your spine has joints, too.But joints are more than bones. They include the soft tissues around them, such as cartilage, tendons and ligaments. Cartilage is the hard slippery flexible tissue that covers the ends of your bones at a joint. Tendons are tough, flexible bands tha… Kidney Diseases You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters. It goes to your bladder, which stores the urine until you go to the bathroom.Most kidney diseas… Raynaud Phenomenon What is Raynaud phenomenon? Raynaud phenomenon is a condition that affects your blood vessels (the tubes that your blood flows through). It causes your blood vessels to narrow, which decreases blood flow. This is called a Raynaud episode or "attack." The attacks usually affect your fingers and toes, causing them to become cold and numb. They may also change color, usually to white or blue. These attacks happen in re…