Systemic Lupus Erythematosus

Body Systems Autoimmune / Immunology Systemic Lupus Erythematosus
Autoimmune Clinical reference

Systemic Lupus Erythematosus

SLE is a multisystem autoimmune disease. SLICC/ACR criteria. Major manifestations: malar rash, nephritis, arthritis, serositis, cytopenias, neuropsychiatric lupus. Anti-dsDNA and low complement track disease activity.

SLE lupus systemic lupus lupus nephritis
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What is lupus?Lupus is a chronic (long-lasting) type of autoimmune disease. Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain.There are several types of lupus:Systemic lupus erythematosus (SLE) is the most common type. It can be mild o…

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Lupus What is lupus?Lupus is a chronic (long-lasting) type of autoimmune disease. Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain.There are several types of lupus:Systemic lupus erythematosus (SLE) is the most common type. It can be mild o… Joint Disorders What are joints?Your joints are places where two or more bones come together. Your shoulders, elbows, hips, knees, and knuckles are all joints. Your spine has joints, too.But joints are more than bones. They include the soft tissues around them, such as cartilage, tendons and ligaments. Cartilage is the hard slippery flexible tissue that covers the ends of your bones at a joint. Tendons are tough, flexible bands tha… Kidney Diseases You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters. It goes to your bladder, which stores the urine until you go to the bathroom.Most kidney diseas… Raynaud Phenomenon What is Raynaud phenomenon? Raynaud phenomenon is a condition that affects your blood vessels (the tubes that your blood flows through). It causes your blood vessels to narrow, which decreases blood flow. This is called a Raynaud episode or "attack." The attacks usually affect your fingers and toes, causing them to become cold and numb. They may also change color, usually to white or blue. These attacks happen in re…